(616) 795-9444    |     email us    |     youtube

Materials, Mixing and Blending

Materials, Mixing and Blending

This video provides a functional overview of the raw materials commonly used in oral solid dose manufacturing, as well as the functional principles of typical mixing and blending techniques.

Used by Drug Makers, Equipment Manufacturers, College and University Professors, Technical Schools, Training Consultants, Operating Personnel, Maintenance Personnel, Field Service Professionals, and Industry Regulators.

Narrative Excerpts

"...diluents are used to bulk out the formulation to provide a dosage form of suitable size to suit patient or manufacturing requirements. Typical diluents are; Lactose, Microcrystalline Cellulose, Dicalcium Phosphate Anhydrous, Mannitol and Sucrose..."

"...common examples of binders in wet granulation are; Hydroxypropylmethylcellulose, Pregelatinised Starch and Povidone also known as Polyvinylpyrrolidone or PVP.  In direct compression, dry binders with a very high degree of deformation properties are used, such as microcrystalline cellulose..."

"...the success of mixing exercises is usually determined by sampling. The sample size should reflect the size of the finished product with the number and position of samples taking into account the batch size and the blending operation.  Sampling from the bulk blend should be supplemented with samples throughout the compression run to take into account possible demixing or segregation..."

"...raw materials and blends often compact upon storage or transport forming agglomerates or clumps which impact upon efficient blending and even distribution of the blend components. This can be mitigated by sieving or screening prior to dispensing to break down agglomerates or clumps..."

Subscription

Videos are securely served via the Product Animations LMS. Please contact us for availability and subscription options.

Contact Us

Custom Video

Can't find video for your machine?

Request a Proposal

Custom Course

Can't find course for your machine?

Request a Proposal

Contact Us

How can we serve you?

General Inquiries